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Original research
Systematic druggable genome-wide Mendelian randomisation identifies therapeutic targets for Alzheimer’s disease

Authors

  • Wei-Ming Su Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, China Institute of Brain Science and Brain-inspired Technology, West China Hospital, Sichuan University, Chengdu, Sichuan, China PubMed articlesGoogle scholar articles
  • Xiao-Jing Gu Department of Mental Health Center, West China Hospital, Sichuan University, Chengdu, China PubMed articlesGoogle scholar articles
  • Meng Dou Chengdu Computer Application Institute, Chinese Academy of Sciences, Chengdu, China PubMed articlesGoogle scholar articles
  • Qing-Qing Duan Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, China Institute of Brain Science and Brain-inspired Technology, West China Hospital, Sichuan University, Chengdu, Sichuan, China PubMed articlesGoogle scholar articles
  • Zheng Jiang Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, China Institute of Brain Science and Brain-inspired Technology, West China Hospital, Sichuan University, Chengdu, Sichuan, China PubMed articlesGoogle scholar articles
  • Kang-Fu Yin Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, China Institute of Brain Science and Brain-inspired Technology, West China Hospital, Sichuan University, Chengdu, Sichuan, China PubMed articlesGoogle scholar articles
  • Wei-Chen Cai Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, China Institute of Brain Science and Brain-inspired Technology, West China Hospital, Sichuan University, Chengdu, Sichuan, China PubMed articlesGoogle scholar articles
  • Bei Cao Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, China Institute of Brain Science and Brain-inspired Technology, West China Hospital, Sichuan University, Chengdu, Sichuan, China PubMed articlesGoogle scholar articles
  • Yi Wang Department of Pathophysiology, West China College of Basic medical sciences & Forensic Medicine, Sichuan University, Chengdu, China PubMed articlesGoogle scholar articles
  • Yong-Ping Chen Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, China Institute of Brain Science and Brain-inspired Technology, West China Hospital, Sichuan University, Chengdu, Sichuan, China PubMed articlesGoogle scholar articles
  1. Correspondence to Professor Yong-Ping Chen, Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, China; Yongping.chen{at}wchscu.cn
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Citation

Su W, Gu X, Dou M, et al
Systematic druggable genome-wide Mendelian randomisation identifies therapeutic targets for Alzheimer’s disease
Journal of Neurology, Neurosurgery & Psychiatry 2023;94:954-961.

Publication history

  • Received January 20, 2023
  • Accepted June 5, 2023
  • First published June 22, 2023.
Online issue publication 
October 12, 2023

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© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.